Method and apparatus for flow cytometry linked with...

H - Electricity – 01 – J

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H01J 49/26 (2006.01) G01J 3/443 (2006.01) G01N 15/14 (2006.01)

Patent

CA 2561007

An apparatus (100) for sequentially analyzing particles such as single cells or single beads, by spectrometry. The apparatus, an elemental flow cytometer, includes means (102) for sequential particle introduction, means (104) to vaporize, atomize and excite or ionize the particles, or an elemental tag associated with an analyte on the particles, and means (106) to analyze the elemental composition of the vaporized, atomized and excited or ionized particles, or an elemental tag associated with the particles. Methods for sequentially analyzing particles such as singe cells or single beads by spectrometry are also described.

Un appareil (100) d'analyse séquentielle de particules, notamment de cellules simples ou de billes par spectrométrie. L'appareil, un cytomètre d'écoulement élémentaire, comprend un module (102) d'introduction de particules séquentielle, un module (104) de vaporisation, d'atomisation et d'excitation ou ionisation des particules, ou une étiquette élémentaire associée à un substrat à analyser sur les particules et un module (106) d'analyse de la composition élémentaire des particules vaporisées, atomisées et excitées ou ionisées, ou une étiquette élémentaire associée aux particules. Des procédés d'analyse séquentielle de particules, notamment des cellules simples ou des billes simples par spectrométrie font également l'objet de cette invention.

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