Peptides for use in wound treatment

Details Peptides for use in wound treatment Peptides for use in wound treatment

A - Human Necessities

61

K

A61K 38/39 (2006.01) A61K 38/04 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61L 15/16 (2006.01) A61L 15/44 (2006.01) C07K 5/103 (2006.01) C07K 14/78 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2227046

The invention provided wound treatment compositions comprising from 10-6% to 1.0% w/w of one or more peptides, wherein the peptides are from 3 to 30 amino acid residues long and comprise the sequence Gly-Pro-Ala. Preferably, the peptides comprise the sequence Gly-Pro-Ala-Gly, more preferably at the N-terminus. The peptides exhibit a chemotactic effect towards fibroblasts.

L'invention porte sur des compositions pour le traitement des plaies; elles renferment de 10-6 % à 1,0 % en poids d'un ou de plusieurs peptides; ceux-ci contiennent de 3 à 30 amino-acides, avec la séquence Gly-Pro-Ala. On privilégie les peptides renfermant la séquence Gly-Pro-Ala-Gly, et de préférence sur le N terminal. Les peptides exercent un effet chimiotactique vis-à-vis des fibroblastes.

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