Retinal toxicity screening methods

G - Physics – 01 – N

Patent

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G01N 33/50 (2006.01)

Patent

CA 2550312

The present invention relates to methods for characterizing a test agent using a fluorescently detectable .alpha.v.szlig.3 and .alpha.v.beta.5 integrin specific agent and a retinal pigment epithelial cell. The invention further relates to kits having a fluorescently detectable .alpha.v.beta.3 and .alpha.v.beta.5 integrin specific agent and a retinal pigment epithelial cell.

L'invention concerne des méthodes permettant de caractériser un agent d'essai à l'aide d'un agent spécifique des intégrines v?.szlig.¿3? et ¿v5 détectable par fluorescence et une cellule épithéliale pigmentaire rétinienne. L'invention concerne également des kits comprenant ledit agent spécifique des intégrines v.szlig.3 et v5 détectable par fluorescence et une cellule épithéliale pigmentaire rétinienne.?¿

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