Monoclonal antibody 3-6-a specific to surface of dendritic...

Details Monoclonal antibody 3-6-a specific to surface of dendritic... Monoclonal antibody 3-6-a specific to surface of dendritic...

C - Chemistry, Metallurgy

12

N

C12N 5/20 (2006.01) C07K 14/74 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12N 15/12 (2006.01) C12N 15/70 (2006.01) C12N 15/85 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2301024

Disclosed is the monoclonal antibody, 3-6-A, which binds to the extracellular region of a DM .alpha. and the hybridoma cell, KHB-DM,with a Deposition No. of KCTC-0485BP, which produces the monoclonal antibody 3-6-A. The monoclonal antibody shows potent binding capacity and exclusive specificity to dendritic cells only, among the peripheral blood leukocytes.

L'invention concerne l'anticorps monoclonal 3-6-A, qui se lie avec la région extracellulaire d'une protéine DM.alpha.. Elle concerne en outre la cellule hybridome KHB-DM, (numéro de dépôt KCTC-0485BP pour le dépôt dans la Collection coréenne des cultures types à l'Institut coréen de recherches en bioscience et biotechnologie), qui produit l'anticorps monoclonal 3-6-A. Cet anticorps a une puissante capacité de liaison et une spécificité exclusive propre aux seules cellules dendritiques, parmi les leucocytes du sang périphérique.

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