Method to diagnose and treat degenerative joint disease

Details Method to diagnose and treat degenerative joint disease Method to diagnose and treat degenerative joint disease

C - Chemistry, Metallurgy

12

Q

C12Q 1/37 (2006.01) A61K 31/397 (2006.01) A61K 31/43 (2006.01) A61K 31/545 (2006.01) A61K 31/65 (2006.01) A61K 38/55 (2006.01) A61P 19/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2438744

Disclosed are methods for detecting and treating joint disease. The methods of diagnosis include determining increased expression of enzymes that are upregulated during the progress of joint and ligament inflammation and degeneration. In addition, disclosed are methods of treating the disease including inhibiting the activity of responsible proteases.

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