C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2572833
This invention comprises the novel compounds of formula (I) wherein R1 , R2, R3, X and Y have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Cette invention porte sur les nouveaux composés représentés par la formule (I), dans laquelle R1 , R2, R3, X et Y ont des significations définies. Ces composés possèdent une activité enzymatique d'inhibition d'histone déacétylase. L'invention porte aussi sur leur préparation, des compositions les contenant et leur utilisation en tant que médicaments.
Angibaud Patrick Rene
Arts Janine
Pilatte Isabelle Noelle Constance
Roux Bruno
Ten Holte Peter
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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