C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 217/24 (2006.01) A61K 31/472 (2006.01) A61P 9/00 (2006.01) A61P 25/00 (2006.01) A61P 27/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2728137
The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
Cette invention concerne des isoquinolines et isoquinolinones substituées de formule (I) utilisées dans le traitement et/ou la prévention des maladies associées avec la Rho-kinase et/ou la phosphorylation par lintermédiaire de la Rho-kinase de la phosphatase des chaînes légères de myosine, et des compositions contenant ces types de composés.
Duclos Olivier
Jeannot Frederic
Kleemann Heinz-Werner
Loehn Matthias
Lorenz Katrin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
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