Compositions for treating allergic disorders using (-)...

Details Compositions for treating allergic disorders using (-)... Compositions for treating allergic disorders using (-)...

A - Human Necessities

61

K

A61K 31/495 (2006.01)

Patent

CA 2145410

Methods and compositions are disclosed utilizing optically pure (-) cetirizine for the treatment of seasonal and perennial allergic rhinitis in humans while avoiding the concomitant liability of adverse effects associated with the racemic mixture of cetir- izine. The optically pure (-) isomer is also useful for the treatment of allergic asthma and chronic and physical urticaria. (-) Cetiri- zine is an inhibitor of eosinophil chemotaxis and is therefore useful in the treatment of other conditions related to eosinophilia such as allergic asthma, seasonal allergic rhinitis, atopic dermatitis, some parasitic diseases, some chronic obstructive lung diseas- es and certain gastrointestinal and genitourinary disorders.

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