Multi-unit pulsatile delivery system

A - Human Necessities – 61 – M

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128/104

A61M 37/00 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2031864

ARC 1586 MULTI-UNIT PULSATILE DELIVERY SYSTEM ABSTRACT OF THE DISCLOSURE The present invention is directed to an active agent dispenser for use in a fluid-containing environment, which dispenser comprises a rigid housing (20), a plurality of movable active agent units (26) (28)(30)(32) and (34), filling a portion of the housing, a fluid- activated driving member (38) for dispensing the active agent units filling the remainder of the housing, and an active agent unit outlet means (22). The dispenser may optionally also include an initial active agent tablet (24), a density element (36), and/or an inert layer (40). In the present invention, each active agent unit is comprised of an active agent dosage or filling contained within a fluid-impermeable cup-shaped member, the cup-shaped members being oriented within the housing with the base of the cup-shaped members facing the outlet means (22).

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