Catalytic asymmetric desymmetrization of meso compounds

C - Chemistry – Metallurgy – 07 – B

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C07B 53/00 (2006.01) C07C 67/08 (2006.01) C07C 69/34 (2006.01) C07C 69/74 (2006.01) C07C 69/753 (2006.01) C07D 487/08 (2006.01) C07D 493/08 (2006.01)

Patent

CA 2405535

The present invention relates to methods for the synthesis of chiral non- racemic products, e.g., enantiomerically-enriched hemiesters, from prochiral starting materials, e.g., meso anhydrides. The present invention also relates to catalysts for the aforementioned methods, and methods for synthesizing these catalysts.

L'invention porte sur des procédés de synthèse de produits chiraux non racémiques, par exemple des hémiesters enrichis en énantiomères, à partir de matériaux de départ prochiraux tels que desméso anhydrides. L'invention porte également sur des catalyseurs utilisés dans les susdits procédés, et sur des procédés de synthèse desdits catalyseurs.

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