Biomarkers and methods for identification of agents useful...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) A01K 67/027 (2006.01) A01K 67/033 (2006.01) C12N 5/10 (2006.01)

Patent

CA 2632052

Potential therapeutic, agent for the prevention, treatment or amelioration of an affective disorder, such as a bipolar disorder, depression or anxiety disorder are identified. Also provided are methods for diagnosing and monitoring affective disorders. The methods are based on changes in expression of one or more genes that are differentially expressed in affective disorders.

L'invention permet d'identifier des agents thérapeutiques potentiels pour la prévention, le traitement ou l'amélioration des troubles affectifs, tel que les troubles bipolaires, la dépression ou les troubles anxieux. L'invention concerne également des méthodes permettant de diagnostiquer et de surveiller des troubles affectifs. Ces méthodes sont basées sur des changements d'expression d'un ou de plusieurs gènes qui sont exprimés de façon différentielle dans les troubles affectifs.

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