Long lasting fusion peptide inhibitors for hiv infection

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/16 (2006.01) A61K 38/16 (2006.01) A61P 31/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2448891

The present invention relates to C34 peptide derivatives that are inhibitors of viral infection and/or exhibit antifusogenic properties. In particular, this invention relates to C34 derivatives having inhibiting activity against human immunodeficiency virus (HIV), respiratory syncytial virus (RSV), human parainfluenza virus (HPV), measles virus (MeV), and simian immunodeficiency virus (SIV) with long duration of action for the treatment of the respective viral infections.

Cette invention se rapporte à des dérivés peptidiques C34 qui constituent des inhibiteurs des infections virales et/ou possèdent des propriétés antifusogéniques. Cette invention concerne en particulier des dérivés C34 ayant une action inhibitrice contre le virus de l'immunodéficience humaine (HIV), le virus respiratoire syncytial (RSV), le virus de la para-influenza humain (HPV), le virus de la rougeole (MeV) et le virus de l'immunodéficience simienne (SIV) avec longue durée d'action pour le traitement des infections virales correspondantes.

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