Compositions and methods for control of reactivity between...

Details Compositions and methods for control of reactivity between... Compositions and methods for control of reactivity between...

G - Physics

01

N

G01N 33/569 (2006.01) G01N 33/558 (2006.01)

Patent

CA 2190109

Compositions, devices and methods for the detection of target microorganisms, such as by a visual immunoprecipitation assay, where the detection requires the migration of the target microorganisms (typically a target microorganism- antibody-detection reagent complex) along a lateral flow membrane of a diagnostic device. The present invention permits such detection by inhibiting the agglutination, or other aggregation, of target microorganisms (and particularly target microorganisms bound to an antibody-detection reagent) while the microorganisms are migrating along the lateral flow membrane.

Compositions, dispositifs et procédés de détection de micro-organismes cibles, à l'aide d'une détermination par immunoprécipitation visuelle par exemple, ladite détection exigeant la migration des micro-organismes cibles (typiquement un complexe anticorps de micro-organisme cible-réactif de détection) le long d'une membrane à écoulement latéral d'un dispositif de diagnostic. Cette invention permet d'effectuer cette détection puisqu'elle empêche les micro-organismes cibles de s'agglutiner ou de se regrouper d'une quelconque manière (et plus particulièrement les micro-organismes cibles liés à un anticorps réactif de détection) alors que les micro-organismes migrent le long de la membrane à écoulement latéral.

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