Prostaglandin derivatives for treating gastrointestinal...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/557 (2006.01) A61K 31/558 (2006.01) A61P 1/04 (2006.01) A61P 1/08 (2006.01) A61P 1/14 (2006.01)

Patent

CA 2577284

The present invention relates to a method for the long term treatment of gastrointestinal disorders in a human subject, which comprises administering an effective amount of a halogenated prostaglandin compound and/or its tautomer to the subject. The method induces substantially no electrolyte shifting during the term of the treatment. The compound used in the present invention can improve quality of life in the human subjects with gastrointestinal disorders, are similarly effective in treating male and female human subjects, and also effective in a human subject aged even 65 years and older.

La présente invention a pour objet une méthode de traitement à long terme de troubles gastro-intestinaux chez un sujet humain. Ledit traitement comprend l'administration d~une quantité significative d~un dérivé halogéné de prostaglandine et/ou d~un tautomère dudit dérivé au sujet. La méthode n~induit pas de migration notable d~électrolyte au cours de la durée du traitement. Les composés utilisés dans la présente invention peuvent améliorer la qualité de vie de patients humains sujets à des troubles gastro-intestinaux, présentent une efficacité de traitement similaire chez l~homme et la femme, et restent efficients chez des patients humains âgés de 65 ans ou plus.

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