Stent for liberating drug

Details Stent for liberating drug Stent for liberating drug

A - Human Necessities

61

L

A61L 31/16 (2006.01) A61F 2/06 (2006.01) A61F 2/90 (2006.01) A61K 9/70 (2006.01) A61K 31/196 (2006.01) A61L 31/04 (2006.01) A61L 31/06 (2006.01) A61L 31/10 (2006.01) A61L 31/14 (2006.01) A61M 31/00 (2006.01)

Patent

CA 2179304

A stent according to the present invention is adapted to be introduced into a vascular system such as blood vessels. The stent includes a stent body produced by weaving or knitting a fiber containing a drug and made of a low-melting biodegradable polymer into a tubular shape, or coating a drug-containing low- melting biodegradable polymer on a stent body. When the stent is introduced into the vascular system, the drug contained therein is dosed in a locally limited region of the vascular system. The low-melting biodegradable polymer used has a melting point of 80° C or lower and is at least one compound selected from the group consisting of poly-.epsilon.-caprolactone, poly-D, L-deca-lactone, poly-dioxane and a copolymer thereof.

Extenseur endovasculaire libérant un médicament destiné à être introduit, par exemple, dans les vaisseaux sanguins et obtenu: par tricotage ou tissage sous forme de tube d'une fibre d'un polymère biodégradable à bas point de fusion contenant un médicament et n'affectant pas l'efficacité pharmacologique dudit médicament; ou application sur le corps d'un extenseur d'un revêtement constitué d'un polymère biodégradable à bas point de fusion contenant un médicament. Lors de l'introduction de l'extenseur dans un vaisseau, le médicament est libéré par le polymère biodégradable et administré localement. Le polymère présente un point de fusion de 80~ ou inférieur et comporte au moins un élément sélectionné parmi la poly-.epsilon.-caprolactone, la poly-D,L-décanolactone, la polydioxanone ou leurs copolymères.

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