C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/18 (2006.01) A61K 38/03 (2006.01) A61K 38/55 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C12Q 1/37 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2194352
This invention relates to methods and compositions for early diagnosis, monitoring and treatment of cartilage degenerative conditions including forms of arthritis and arthropathy, using an antibody which recognizes a peptide comprising the sequence FFGVG... generated by cleavage of cartilage aggrecan at the site N341-F342.
L'invention concerne des méthodes et des compositions utilisées pour le diagnostic précoce, la surveillance et le traitement de dégénérescences des cartilages, y compris des formes d'arthrites et d'arthropathie, au moyen d'un anticorps qui reconnaît un peptide comprenant la séquence FFGVG... produite par clivage de l'aggrécane du cartilage sur le site N341-F342.
Oyen Wiggs Green & Mutala Llp
The University Of Melbourne
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