C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/16 (2006.01) A61K 31/438 (2006.01) A61K 31/5377 (2006.01) A61P 25/00 (2006.01) C07D 471/10 (2006.01) C07D 491/10 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2674518
The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I), wherein R1 to R5, R5', X, Y and A are as defined in the specification.
La présente invention concerne de nouveaux dérivés de spiropipéridine constituant des antagonistes du récepteur V1a, ainsi que leur fabrication, des compositions pharmaceutiques les contenant et leur utilisation comme médicaments. Les composés actifs selon l'invention sont utiles pour prévenir et/ou traiter l'anxiété et les troubles dépressifs et d'autres maladies. L'invention concerne en particulier des composés représentés par la formule générale (I), dans laquelle R1 à R5, R5', X, Y et A sont tels que définis dans la description.
Bissantz Caterina
Grundschober Christophe
Masciadri Raffaello
Ratni Hasane
Rogers-Evans Mark
Borden Ladner Gervais Llp
F.hoffmann-La Roche Ag
LandOfFree
Spiro-piperidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Spiro-piperidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Spiro-piperidine derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1830008