Agent for lowering endothelin levels

Details Agent for lowering endothelin levels Agent for lowering endothelin levels

A - Human Necessities

61

K

A61K 31/138 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01) A61P 9/14 (2006.01) A61P 13/08 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2353808

The present invention relates to a new medical use of triphenylethylene antiestrogen toremifene or a pharmaceutically acceptable thereof for lowering endothelin-1 levels in mammals, and for the prevention or treatment of endothelin mediated diseases.

L'invention concerne une nouvelle utilisation médicale de torémifène anti-oestrogène triphényléthylène ou de sel correspondant pharmaceutiquement acceptable, qui permet d'abaisser les niveaux d'endothéline-1 chez les mammifères et qui peut être utilisé pour la prévention ou le traitement des maladies dont la médiation est assurée par l'endothéline.

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