Spectrophotometric examination of tissue of small dimension

A - Human Necessities – 61 – B

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A61B 10/00 (2006.01) A61B 5/00 (2006.01) G01N 21/49 (2006.01) G01N 21/03 (2006.01) G01N 21/31 (2006.01)

Patent

CA 2154062

A system (10) for examination of a volume of biological tissue using visible or infra-red radiation includes a spectrophotometer (18), an optical medium (12) having selectable scattering and absorptive properties, and a processor (35) for determining a physiological property of the examined tissue. The spectrophotometer (18) includes a light source (21) for introducing radiation at an optical input port (19) and a detector (23) for detecting radiation that has migrated through a path from the input port ( 19) to an optical detection port (21). The biological tissue is positioned into a photon migration path inside the optical medium (12) to create a tissue medium optical path. The optical medium (12) is adapted to limit substantially escape of photons from the tissue. The processor (35) determines tissue properties based on the detected optical property of the tissue-medium optical path and the selectable properties of the optical medium (12).

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