C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/56 (2006.01) G01N 33/86 (2006.01)
Patent
CA 2205180
The present invention provides an in vitro method useful for the diagnosis of a thrombotic disorder in a subject, having or at risk of having the disorder. Specifically, the disorder exemplified herein is associated with activated protein C (APC) resistant Factor V and Va. The clotting time of a test sample is analyzed in the presence and absence of activated protein C (APC) and compared with a standard reference sample in order to diagnose the subject.
La présente invention concerne une méthode in vitro utile pour diagnostiquer des troubles thrombotiques chez un sujet présentant ou susceptible de présenter ces troubles. Spécifiquement, l'anomalie considérée dans cette invention est associée avec le facteur V et Va résistant à la protéine C activée (APC). Le temps de coagulation d'une prise d'essai est analysé en présence et en l'absence de protéine C activée (APC) et comparé à un échantillon de référence type en vue d'établir le diagnostic pour l'individu considéré.
Griffin John H.
Le Dzung T.
Rapaport Samuel I.
Fetherstonhaugh & Co.
The Regents Of The University Of California
The Scripps Research Institute
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