Peptides containing n-substituted l-amino acids for...

Details Peptides containing n-substituted l-amino acids for... Peptides containing n-substituted l-amino acids for...

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

K

IPC codes

C07K 14/47 (2006.01) A61K 38/17 (2006.01) A61P 25/28 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Type

Patent

Patent number

CA 2378779

Description

Chemical compounds and compositions are disclosed which comprise peptides capable of binding to .beta.-strand structures to form .beta.-sheets, said peptides being selectively N.alpha.-substituted to prevent further .beta.- strand association. The peptides are useful for preventing .beta.-strand association.

La présente invention concerne des composés chimiques et des compositions qui comprennent des peptides capables de se lier à des structures de brin .beta. de façon à former des feuillets .beta.. Ces peptides sont sélectivement N.alpha.-substitués de façon à empêcher une autre association de brins .beta.. Ces peptides conviennent pour empêcher l'association de brins .beta..

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