G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2555656
The invention relates to a method for assessing the proliferative state of cells in a human or non human biological sample, comprising using Chromatin Assembly Factor-1 (CAF-1 in short) subunits as proliferation markers. Application for cancer prognosis or diagnosis and monitoring tumor response in therapy.
La présente invention a trait à un procédé permettant l'évaluation de l'état de prolifération cellulaire dans un échantillon biologique humain ou non humain, comprenant des sous-unités de facteur d'assemblage en chromatine (CAF-1) comme marqueurs de la prolifération. L'invention est utile pour le pronostic ou le diagnostic du cancer et le suivi de la réponse tumorale en thérapie.
Almouzni Genevieve
Polo Sophie E.
Theocharis Stamatios E.
Vielh Philippe
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Centre National de La Recherche Scientifique (cnrs)
Institut Curie
Universite Pierre Et Marie Curie (paris Vi)
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