A novel factor-h related protein 5 and antobodies thereto

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) G01N 33/554 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2373414

A novel human factor H-related protein (FHR-5) is disclosed. Included within the scope of the invention are the amino acid sequence of FHR-5, nucleic acid sequences encoding the amino acid sequence of FHR-5 and substantially identical amino acid and nucleotide sequences. Also within the scope of the invention are vectors comprising the nucleotide sequences of the invention, transgenic host cells containing the nucleotide sequences of the invention and antibodies that react with the FHR-5 protein.

L'invention concerne une nouvelle protéine humaine liée au facteur H (FHR-5). L'invention concerne également la séquence d'acides aminés de la FHR-5, les séquences d'acides nucléiques codant la séquence d'acides aminés de la FHR-5 et des séquences nucléotidiques et d'acides aminés sensiblement identiques. L'invention concerne, en outre, des vecteurs comprenant les séquences nucléotidiques de l'invention, des cellules hôtes transgéniques contenant les séquences nucléotidiques de l'invention et des anticorps réagissant contre la protéine FHR-5.

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