Risedronate compositions and their methods of use

A - Human Necessities – 61 – K

Patent

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A61K 31/675 (2006.01) A61P 19/10 (2006.01)

Patent

CA 2564898

A method comprising orally administering to a human or other mammal a pharmaceutical composition comprising from about 65% to about 110% of the cumulative effective dose of risedronate or a pharmaceutically acceptable acid, salt, ester, solvate, or polymorph thereof according to a continuous dosing schedule of one, two, or three consecutive days per month is useful for treating or preventing osteoporosis and other bone metabolic disorders.

Cette invention a pour objet un procédé comprenant l~administration par voie orale, à un être humain ou à un autre mammifère, d~une composition pharmaceutique comprenant entre environ 65 % et environ 110 % de la dose efficace accumulée de risédronate ou d~un acide, d~un sel, d~un ester, d~un solvate ou d~un polymorphe de qualité pharmaceutique, suivant un programme de dosage en continu sur un, deux ou trois jours consécutifs par mois, utile pour le traitement ou la prévention de l~ostéoporose et des autres troubles métaboliques osseux.

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