Liposome composition for reduction of liposome-induced...

Details Liposome composition for reduction of liposome-induced... Liposome composition for reduction of liposome-induced...

A - Human Necessities

61

K

A61K 9/127 (2006.01)

Patent

CA 2517352

A method for reducing complement activation upon in vivo administration of a liposome preparation containing an entrapped therapeutic agent is described. The method involves providing liposomes having a polyethylene-glycol-derived neutral lipopolymer.

Cette invention se rapporte à un procédé qui permet de réduire l'activation du complément lors de l'administration <i>in vivo </i> d'une préparation à base de liposomes contenant un agent thérapeutique piégé. Ce procédé consiste à fournir des liposomes comportant un lipopolymère neutre dérivé de polyéthylène glycol.

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