Combination of a cdk inhibitor and mitoxantrone

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/137 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2503115

A first aspect of the invention relates to a combination comprising a CDK inhibitor and mitoxantrone. A second aspect of the invention relates to a pharmaceutical product comprising a CDK inhibitor and mitoxantrone as a combined preparation for simultaneous, sequential or separate use in therapy. A third aspect of the invention relates to a method of treating a proliferative disorder, said method comprising simultaneously, sequentially or separately administering a CDK inhibitor and mitoxantrone to a subject.

Un premier aspect de l'invention concerne une combinaison comprenant un inhibiteur de CDK et mitoxantrone. Un deuxième aspect de cette invention concerne un produit pharmaceutique contenant un inhibiteur de CDK et mitoxantrone sous forme de préparation combinée dans le but d'une utilisation simultanée, séquentielle ou séparée sur le plan thérapeutique. Un troisième aspect de l'invention concerne une méthode de traitement d'une maladie proliférative, ladite méthode consistant à administrer de façon simultanée, séquentielle ou séparée un inhibiteur de CDK et mitoxantrone à un sujet.

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