Human protein kinases and protein kinase-like enzymes

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/54 (2006.01) A61K 38/45 (2006.01) C07K 14/47 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2401541

The present invention relates to kinase polypeptides, nucleotide sequences encoding the kinase polypeptides, as well as various products and methods useful for the diagnosis and treatment of various kinase-related diseases and conditions. Through the use of a bioinformatics strategy, mammalian members of the PTK's and STK's have been identified and their protein structure predicted.

L'invention porte sur des polypeptides kinases, des séquences nucléotidiques codant pour ces polypeptides kinases et sur différents produits et procédés utiles pour le diagnostic et le traitement de différentes maladies et états liés aux kinases. Grâce à l'utilisation d'une stratégie bioinformatique, on a pu identifier des éléments mammaliens de PTK et STK et en prédire la structure protéique.

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