Method for accelerating the rate of mucociliary clearance

Details Method for accelerating the rate of mucociliary clearance Method for accelerating the rate of mucociliary clearance

A - Human Necessities

61

K

A61K 38/57 (2006.01) A61K 9/72 (2006.01) A61P 11/12 (2006.01)

Patent

CA 2356404

The instant invention provides for a composition and method for using Kunitz- type serine protease inhibitors, e.g., aprotinin or bikunin. for stimulating the rate of mucociliary clearance of mucus and sputum in lung airways of subjects afflicted with mucociliary dysfunctions such as cystic fibrosis.

L'invention concerne une composition et une technique permettant d'utiliser des inhibiteurs de sérine protéase de type Kunitz, par exemple l'aprotinine ou la bikunine, afin de stimuler le débit de clairance mucociliaire du mucus et d'expectoration dans les voies pulmonaires d'un sujet affligé de dysfonctionnements mucociliaires tels que la mucovicidose.

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