A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/38 (2006.01) A61K 8/98 (2006.01) A61L 27/58 (2006.01)
Patent
CA 2609507
The present invention provides a method for the repair of subcutaneous or dermal tissue in a subject, comprising in one aspect the injection of a suspension of allogeneic dermal fibroblasts into the subject. By injecting a suspension of allogeneic cells, the invention provides, for example, long-term augmentation of the subadjacent tissue without the disadvantages that accompany the preparation and/or use of presently available materials such as autologous fibroblasts cells or collagen. According to a first aspect of the invention there is provided a method for the augmentation of subcutaneous or dermal tissue in a subject, which method comprises the steps of: (i) providing a suspension of allogeneic dermal fibroblasts; and (ii) injecting an effective volume of the suspension into tissue subadjacent to the subcutaneous or dermal tissue so that the tissue is augmented. The method is preferably cosmetic.
La présente invention concerne une méthode pour réparer le tissu sous-cutané ou dermique chez un sujet, et comprend dans un aspect l'injection dans le sujet d'une suspension de fibroblastes allogènes dermiques. En injectant une suspension de cellules allogènes, l'invention permet, par exemple, d'augmenter à long terme le tissu sous-jacent sans les inconvénients qui accompagnent la préparation et/ou l'utilisation des matériaux disponibles actuellement tels que les cellules de fibroblastes autologues ou le collagène. Un premier aspect de l'invention porte sur une méthode pour augmenter le tissu sous-cutané ou dermique chez un sujet, ladite méthode comportant les étapes : (i) de fourniture d'une suspension de fibroblastes dermiques allogènes ; et (ii) d'injection d'un volume efficace de la suspension dans le tissu sous-jacent au tissu sous-cutané ou dermique afin que le tissu soit augmenté. La méthode est de préférence cosmétique.
Kemp Paul
Leek Mike
Intercytex Limited
Ridout & Maybee Llp
LandOfFree
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