A liquid pharmaceutical formulation comprising nicotine for...

A - Human Necessities – 61 – K

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A61K 31/465 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2471906

A liquid pharmaceutical formulation comprising nicotine in any form for administration to the oral cavity being alkalized by buffering and/or pH regulation. The administration is preferably by spraying and most preferably by spraying under the tongue. A method for manufacturing said formulation. Use of said formulation in therapy, such as therapy for treating addiction to tobacco.

L'invention concerne une préparation pharmaceutique liquide renfermant de la nicotine sous n'importe quelle forme, alcalinisée par tamponnage et/ou par régulation du pH, destinée à être administrée par voie orale. Cette préparation est administrée, de préférence, par pulvérisation et, idéalement, par pulvérisation sublinguale. L'invention concerne également une méthode de fabrication de cette préparation. Cette préparation est utilisée à des fins thérapeutiques, notamment pour le traitement de la dépendance au tabac.

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