Use of nk-1 receptor antagonists for treating movement...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/675 (2006.01) A61K 31/00 (2006.01) A61K 31/395 (2006.01) A61K 31/435 (2006.01) A61K 31/438 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/535 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) C07D 211/56 (2006.01) C07D 491/10 (2006.01)

Patent

CA 2273809

The present invention provides the use of an orally active, long acting, CNS- penetrant NK-1 antagonist for the manufacture of a medicament for oral administration for the treatment or prevention of movement disorders, methods of treatment using such a NK-1 receptor antagonist and pharmaceutical compositions comprising it.

La présente invention a pour objet l'utilisation d'un antagoniste du NK-1, à action prolongée, agissant sur le système nerveux central; et administré par voie orale, dans la fabrication d'un médicament pouvant être administré par voie orale permettant de traiter ou de prévenir les diskynésies. L'invention traite également de procédés de traitement à l'aide d'un antagoniste du récepteur NK-1 et de compositions pharmaceutiques comprenant cet antagoniste.

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