Human tumor-associated membrane protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2286390

The present invention provides a human tumor-associated membrane protein (TAMPH) and polynucleotides which identify and encode TAMPH. The invention also provides expression vectors, host cells, antibodies and antagonists. The invention also provides methods for the prevention and treatment of diseases associated with expression of TAMPH, as well as diagnostic assays.

Cette invention a trait à une protéine membranaire associée à une tumeur chez l'homme (TAMPH) ainsi qu'à des polynucléotides l'identifiant et la codant. Elle porte également sur des vecteurs d'expression, des cellules hôtes, des anticorps et des antagonistes. Elle concerne, de surcroît, des méthodes prophylactiques et thérapeutiques relatives à des troubles associés à l'expression de la protéine TAMPH, ainsi que des épreuves diagnostiques.

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