Cannabinoid crystalline derivatives and process of...

Details Cannabinoid crystalline derivatives and process of... Cannabinoid crystalline derivatives and process of...

C - Chemistry, Metallurgy

07

D

C07D 311/80 (2006.01)

Patent

CA 2504743

.DELTA. 9 tetrahydrocannabinol (THC) esters comprising the reaction product of THC with at least one aryl sulfonyl chloride in the presence of at least one tertiary amine. The resulting aryl sulfonic THC esters are highly crystalline and stable at room temperature in air, allowing for indefinite storage. The aryl sulfonic THC esters can be recrystallized for purification, and then hydrolyzed to recover the purified THC.

L'invention concerne des esters de delta-9 tétrahydrocannabinol (THC) comprenant le produit de la réaction entre du THC et au moins un chlorure d'aryl sulfonyl en présence d'au moins une amine tertiaire. Les esters de THC sulfoniques aryle sont hautement cristallins et stables à température ambiante dans l'air, permettant ainsi un stockage illimité. Ces esters de THC sulfoniques aryle peuvent être recristallisés pour être purifiés, puis hydrolysés pour récupérer le THC purifié.

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