Novel process for preparation of clonidine derivatives

Details Novel process for preparation of clonidine derivatives Novel process for preparation of clonidine derivatives

C - Chemistry, Metallurgy

07

C

C07C 335/16 (2006.01) C07D 233/50 (2006.01) C07D 239/14 (2006.01) C07D 243/04 (2006.01)

Patent

CA 2158763

A novel process preparing clonidine derivatives has been discovered which is shorter, less expensive and safer than previously known methods. A new thiourea complex of formula (I) wherein: Ar is a phenyl or naphthyl and unsubstituted or substituted with one or more moieties selected from the group consisting of: Cl, F, Br, I, C1 to C4 alkyl, aryl, C1 to C4 alkoxy or arylalkoxy; NO2 is in the para or ortho position; and n is 1 to 4, has also been discovered which can be directly cyclized to produce the corresponding heterocyclic product.

On a découvert un nouveau procédé de préparation de dérivés de clonidine qui est plus court, moins cher, et plus sûr que les procédés antérieurs, connus. On a également découvert un nouveau complexe de thiourea de la formule (I) dans laquelle: Ar représente un phényle ou naphthyle, non substitué ou substitué par une ou plusieurs fractions sélectionnées dans le groupe composé de: Cl, F, Br, I, alkyle C¿1? à C¿4?, aryle, alcoxy C¿1? à C¿4? ou arylalcoxy; NO¿2? se trouve en position para ou ortho; et n vaut de 1 à 4, ce complexe pouvant être directement cyclisé pour obtenir le produit éthérocyclique correspondant.

Affiliated with

Also associated with

Rating

Novel process for preparation of clonidine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel process for preparation of clonidine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel process for preparation of clonidine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1835696