Cyclodextrins as suspending agents for pharmaceutical...

A - Human Necessities – 61 – K

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A61K 47/40 (2006.01) A61K 31/405 (2006.01) A61K 31/4166 (2006.01) A61K 31/4174 (2006.01) A61K 31/437 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2206348

The present invention relates to stable aqueous suspension of drugs suitable for therapeutic administration without requiring solubilization or complexation of those drugs. The suspensions are stabilized with cyclodextrin type suspending agents. Stabilized suspensions of corticosteroids which employ these suspending agents are useful for therapeutic treatment of the eye, ear, or nose.

La présente invention concerne des suspensions aqueuses stables de médicaments convenant à une administration thérapeutique sans recours à la solubilisation ou à la formation de complexe de ces médicaments. Lesdites solutions sont stabilisées grâce à des agents de suspension du type de la cyclodextrine. Des suspensions de corticostéroïdes stabilisées à l'aide de ces agents de suspension servent au traitement thérapeutique des yeux, des oreilles et du nez.

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