Method of reducing the growth of lactobacilli in a process...

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 7/06 (2006.01)

Patent

CA 2655301

A method of controlling microorganisms such as lactobacilli metabolism in mash in an ethanol production facility includes adding to the mash an effective amount to control such microorganisms of one or more of a substantially water insoluble pristinamycin-type antimicrobial agent, a substantially water insoluble polyether ionophore antimicrobial agent, or both, wherein the term "substantially water insoluble" means the antimicrobial agent has a solubility in pure water at 20° C of 0.1 grams per liter or less, and wherein at least a portion of the substantially water insoluble antimicrobial agent(s) is added to the mash in the form of: 1) an organic liquid comprising at least one organic solvent having said substantially water insoluble antimicrobial agent(s) dissolved therein, said organic liquid advantageously comprising more than 1 gram per liter of said antimicrobial agent(s); 2) particles comprising said substantially water insoluble antimicrobial agent(s) and having a weight mean average diameter of less than 5 microns; or 3) both.

L'invention concerne un procédé de régulation du métabolisme de microorganismes tels que des lactobacillus dans un produit malaxé dans une unité de production d'éthanol consistant à ajouter au produit malaxé une quantité efficace pour réguler de tels microorganismes d'un agent antimicrobien de type pristinamycine pratiquement insoluble dans l'eau, d'un agent antimicrobien polyéther ionophore pratiquement insoluble dans l'eau ou des deux, le terme "pratiquement insoluble dans l'eau" signifiant que l'agent antimicrobien a une solubilité dans l'eau pure à 20°C inférieure ou égale à 0,1 gramme par litre et au moins une partie du ou des agents antimicrobiens pratiquement insolubles dans l'eau étant ajoutée au produit malaxé sous la forme: 1) d'un liquide organique comprenant au moins un solvant organique ayant ledit ou lesdits agents antimicrobiens pratiquement insolubles dans l'eau dissous dans celui-ci, ledit liquide organique comprenant avantageusement plus de 1 gramme par litre dudit ou desdits agents antimicrobiens; 2) de particules comprenant ledit ou lesdits agents antimicrobiens pratiquement insolubles dans l'eau et ayant un diamètre moyen en poids inférieur à 5 microns; ou 3) des deux.

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