A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/48 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2604281
The present invention is directed to compositions comprising a nanoparticulate prostaglandin derivative, preferably limaprost or a salt or derivative thereof, having improved bioavailability. The nanoparticulate prostaglandin derivative particles of the composition have an effective average particles size of less than about 2000 nm and are useful in the treatment of ischemic symptoms. The invention also relates to a controlled release composition comprising a prostaglandin derivative, such as limaprost alfadex, or a nanoparticulate prostaglandin derivative, such as limaprost or a salt or derivative thereof, that in operation delivers the drug in a pulsed or bimodal manner for the treatment of ischemic symptoms.
L'invention concerne des compositions contenant un dérivé de prostaglandine nanoparticulaire, de préférence limaprost ou son sel ou dérivé, faisant preuve d'une biodisponibilité améliorée. Les particules du dérivé de prostaglandine nanoparticulaire de la composition présentent une granulomérie moyenne efficace inférieure à environ 2 000 nm et sont utilisées dans le traitement de symptômes ischémiques. L'invention concerne également une composition à libération contrôlée comprenant un dérivé de prostaglandine, notamment limaprost alfadex, ou un dérivé de prostaglandine nanoparticulaire, notamment limaprost ou son sel ou dérivé, permettant d'administrer le médicament par impulsion ou bimode pour le traitement de symptômes ischémiques.
Jenkins Scott
Liversidge Gary
Elan Pharma International Limited
Kirby Eades Gale Baker
LandOfFree
Nanoparticulate and controlled release compositions... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nanoparticulate and controlled release compositions..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nanoparticulate and controlled release compositions... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1836782