C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01)
Patent
CA 2405183
The invention concerns the use of a PyA-(Z)¿x?-pNF group in a substrate for detecting, identifying and/or analysing by fluorometry peptidases or proteases capable of cleaving the or a bond between a PyA and pNF and/or compounds with inhibiting or activating activity with respect to enzymes capable of cleaving said bond.
La présente invention a pour objet l'utilisation d'un reste PyA-(Z)x-pNF dans un substrat à des fins de detection, identification et/ou dosage par fluorescence de peptidases ou protéases susceptibles de cliver la ou une liaison entre PyA et pNF et/ou de composés à activité inhibitrice ou activatrice vis-à-vis d'enzymes capables de cliver cette liaison.
de Rocquigny Hugues
Fournie-Zaluski Marie-Claude
Luciani Nathalie
Roques Bernard Pierre
Centre National de La Recherche Scientifique (c.n.r.s.)
Institut National de La Sante Et de La Recherche Medicale (inser
Robic
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