C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/75 (2006.01) A61K 31/167 (2006.01) A61P 11/00 (2006.01)
Patent
CA 2742902
The present invention relates in general to a compound (activator) which is characterized by a formula selected from the following formulas A, B and/or C or a pharmaceutically acceptable salt thereof. The present invention further relates to pharmaceutical composition comprising the activator(s) of the invention and to their use in the treatment of (for treating) and/or preventing diseases or medical conditions which benefit from an increased transport of hyaluronan across a lipid bilayer. The present invention also relates to a method for manufacturing a pharmaceutical composition comprising the steps of formulating the activator defined herein in a pharmaceutically acceptable form.
De façon générale, cette invention concerne un composé (activateur) caractérisé par une formule prise parmi les formules A, B et/ou C, ou bien un sel de qualité pharmaceutique de ce composé. De plus, linvention concerne une composition pharmaceutique renfermant le ou les activateurs et leur utilisation dans le traitement et/ou la prévention de maladies ou de troubles pour lesquels un transport accru de hyaluronan à travers une bicouche lipidique est bénéfique. Est également décrit un procédé de fabrication dune composition pharmaceutique consistant à formuler lactivateur défini dans le descriptif sous une forme pharmaceutiquement acceptable.
Blake Cassels & Graydon Llp
Universitaetsklinikum Muenster
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