Solid forms of (e) -1- (4- ( (ir, 2s, 3r) -1, 2, 3,...

Details Solid forms of (e) -1- (4- ( (ir, 2s, 3r) -1, 2, 3,... Solid forms of (e) -1- (4- ( (ir, 2s, 3r) -1, 2, 3,...

C - Chemistry, Metallurgy

07

D

C07D 233/64 (2006.01) A61K 31/4164 (2006.01) A61P 29/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2683963

Amorphous and crystalline solid forms of (E)-M (4-((1 R,2S,3R)-1,2,3,4-tertahydroxybutyl)- 1 H-imidazol-2-yl)ethanone oxime are disclosed. These specific solid forms may be used as sphingosite-1 phosphate modulators for treating autoimmune and inflammatory diseases.

L'invention concerne des formes solides amorphes et cristallines de (E)-M (4-((1 R,2S,3R)-1,2,3,4-tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone oxime. Ces formes solides spécifiques peuvent être utilisées en tant que modulateurs de sphingosine-1 phosphate pour traiter des maladies inflammatoires et auto-immunes.

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