Computational subtraction method

Details Computational subtraction method Computational subtraction method

G - Physics

06

F

G06F 19/00 (2006.01)

Patent

CA 2444604

The invention provides a method and system for performing computational subtraction to detect microbes within a host organism. In some aspects, the microbes are pathogens and the system is used to identify sequences belonging to these pathogens which can then be used in methods of diagnosis and treatment. Alternatively, the microbes can be symbiotic organisms, such as commensal or parasitic organisms. Preferably, candidate sequences identified as belonging to a microbe are used to isolate and clone additional sequences from the microbe.

L'invention concerne un procédé et un système permettant d'effectuer une soustraction computationnelle afin de détecter des microbes au sein d'un organisme hôte. Selon certains aspects, les microbes sont des agents pathogènes et le système est utilisé pour identifier des séquences appartenant à ces agents qui peuvent être utilisés dans des méthodes de diagnostic et de traitement. En outre, les microbes peuvent être des organismes symbiotiques, tels que des organismes parasitaires ou commensaux. De préférence, on utilise des séquences candidates identifiées comme appartenant à un microbe pour isoler et cloner des séquences supplémentaires provenant du microbe.

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