Chemically and thermally stable norastemizole formulations

A - Human Necessities – 61 – K

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Details

A61K 47/00 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/454 (2006.01)

Patent

CA 2284705

The present invention relates to chemically and thermally stable pharmaceutical formulations of the potent antihistamine, norastemizole. The compositions are lactose-free, non-hygroscopic, or anhydrous, or comprise large particles or inertly coated norastemizole, or a pharmaceutically acceptable salt thereof, and are stable and easily manufactured.

La présente invention concerne des formulations chimiquement et thermiquement stables de norastémizole qui est un antihistaminique puissant. Ces compositions, ou certains de leurs sels pharmaceutiquement admis, sont exemptes de lactose, sont non hygroscopiques, sont anhydres, comprennent des grandes particules de norastémizole ou du norastémizole enrobé de façon inerte. Les composés de l'invention sont stables et faciles à fabriquer.

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