A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 27/00 (2006.01) A61L 27/28 (2006.01) A61L 27/54 (2006.01)
Patent
CA 2162114
The present invention relates to a bioactive conjugate adapted to coat a metal implant outer surface, which have the following structural formula (I): -R-X-P wherein, R is O or S, adapted to be covalently attached to an implant surface; X is selected from a bond, linear or branched chains of 1 to 30 covalently attached atoms of at least C, N, O, Si or S, rings of 1 to 20 covalently attached atoms of at least C, N, O, Si or S, and a combination thereof; and P is a bioactive molecular moiety which promotes tissue growth, stabilization and integration, and wherein said moiety retains its biological activity. The present invention also relates to a process for the covalent coating of implants with bioactive conjugates.
Mckee Marc D.
Nanci Antonio
Sacher Edward
Savadogo Oumarou
Wuest James
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Universite de Montreal
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