Ptp 1d: a novel protein tyrosine phosphatase

Details Ptp 1d: a novel protein tyrosine phosphatase Ptp 1d: a novel protein tyrosine phosphatase

C - Chemistry, Metallurgy

12

N

C12N 15/55 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/40 (2006.01) C12N 9/16 (2006.01) C12Q 1/42 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2146544

A novel protein tyrosine phosphatase is the protein designated PTP 1D. The PTP 1D protein may be produced by recombi- nant means, for example using a nucleic acid construct encoding the protein as provided herein. Also disclosed is an antibody specific for an epitope of PTP 1D, protein. Methods for identifying compounds which bind to a PTP 1D protein and inhibit or stimulate its enzymatic activity, pharmaceutical compositions comprising PTP 1D, and methods for treating a disease associated with PTP 1D protein using such compositions, are provided.

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