C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/24 (2006.01) A61K 31/4164 (2006.01) A61K 31/4178 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) C07D 233/26 (2006.01) C07D 233/36 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2585535
The invention relates to the bradykinin B1 antagonists of general formula (I), wherein A, Ar, G, Q, R1 and R4 are defined as in claim 1, to the enantiomers, diastereomers, mixtures and salts thereof, especially the physiologically acceptable salts thereof with organic or inorganic acids or bases. The inventive bradykinin B1 antagonists have valuable properties. The invention also relates to the production thereof, to the drugs comprising the pharmacologically effective compounds, to the production thereof and to their use.
L'invention concerne des antagonistes de la bradykinine B1 de formule (I), dans laquelle A, Ar, G, Q, R1 et R4 sont spécifiés dans la revendication 1, leurs énantiomères, leurs diastéréomères, leurs mélanges et leurs sels, en particulier leurs sels phyiologiquement acceptables comprenant des acides ou des bases organiques ou inorganiques, lesquels présentent des propriétés précieuses. L'invention concerne également leur production, des médicaments contenant les composés pharmaceutiquement actifs, leurs production et leur utilisation.
Ceci Angelo
Doods Henri
Hauel Norbert
Kauffmann-Hefner Iris
Peters Stefan
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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