Non-human primate cd4 polypeptides, fusions thereof, dna...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 14/73 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 15/13 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2065010

2065010 9102743 PCTABS00003 The invention relates to a non-human CD4 polypeptide, fragments thereof, immunotoxins comprising said protein, and chimeric proteins comprising said CD4 polypeptide and immunoglobulin light or heavy chain. The invention also relates to the use of said proteins as diagnostic agents and therapeutics. The invention further relates to nucleotide sequences which encode said CD4 polypeptides and the use thereof for expression of the CD4 proteins in recombinant host cells.

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