Human artificial chromosome (hac) vector and human cell...

Details Human artificial chromosome (hac) vector and human cell... Human artificial chromosome (hac) vector and human cell...

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A01K 67/027 (2006.01) A61K 48/00 (2006.01) A61P 3/10 (2006.01) A61P 7/00 (2006.01) A61P 25/16 (2006.01) C12N 5/10 (2006.01) C12N 15/09 (2006.01) C12N 15/64 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2658204

A human artificial chromosome (HAC) vector carrying a centromere derived from a human chromosome, a subtelomere sequence and a telomere sequence; a human cell pharmaceutical or a human cell each comprising the HAC vector; methods for producing the HAC vector and the human cell; and a method for producing a therapeutic protein by using the HAC vector.

La présente invention concerne un vecteur de chromosome artificiel humain (CAH) comportant un centromère dérivé d'un chromosome humain, une séquence de subtélomère et une séquence de télomère, une substance pharmaceutique à base de cellules humaines ou une cellule humaine contenant chacune le vecteur de CAH, des procédés permettant de produire le vecteur de CAH et la cellule humaine, et un procédé permettant de produire une protéine thérapeutique au moyen du vecteur de CAH.

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