A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 25/28 (2006.01) C07K 16/18 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2375104
Disclosed are pharmaceutical compositions and methods for preventing or treating a number of amyloid diseases, including Alzheimer's disease, prion diseases, familial amyloid neuropathies and the like. The pharmaceutical compositions include immunologically reactive amounts of amyloid fibril components, particularly fibril-forming peptides or proteins. Also disclosed are therapeutic compositions and methods which use immune reagents that react with such fibril components.
L'invention concerne des compositions pharmaceutiques et des procédés de prévention ou de traitement d'un certain nombre de maladies amyloïdes, notamment la maladie d'Alzheimer, des maladies à prions, des neuropathies amyloïdes familiales et analogues. Les compositions pharmaceutiques comprennent des quantités immunologiquement réactives de composants de fibrilles amyloïdes, plus particulièrement de peptides ou protéines formant des fibrilles. Font aussi l'objet de cette invention des compositions thérapeutiques et des procédés faisant intervenir des réactifs de l'immunité réagissant aux composants de fibrilles.
Elan Pharma International Limited
Gowling Lafleur Henderson Llp
Neuralab Limited
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