Thio-substituted peptides as inhibitors for...

Details Thio-substituted peptides as inhibitors for... Thio-substituted peptides as inhibitors for...

C - Chemistry, Metallurgy

07

K

C07K 5/062 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07K 5/02 (2006.01) C07K 5/03 (2006.01) C07K 5/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2229434

Peptide compounds of formula (I). Peptides are inhibitors of (matrix) metalloproteinases like collagenase and stromelysin. Furthermore, they inhibit the liberation of tumor necrosis factor .alpha. (TNF.alpha.).

Cette invention se rapporte à des composés peptidiques de formule (I) qui sont des inhibiteurs des métalloprotéases (matricielles) comme le collagène et la stromélysine. Ils inhibent par ailleurs la libération du facteur de nécrose tumorale .alpha. (TNF.alpha.).

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