Aerosolised azole anti fungals

Details Aerosolised azole anti fungals Aerosolised azole anti fungals

A - Human Necessities

61

K

167/158, 167/233

A61K 9/12 (2006.01) A61K 31/40 (2006.01) A61K 31/415 (2006.01)

Patent

CA 2014401

Abstract Aerosolized Azole Antifungals There are described pharmaceutical formulations comprising as active ingredient, an azole antifungal in a form suitable for administration by inhalation. Such formulations include pressurised aerosol formulations, non-pressurised aerosol formulations and solutions/suspensions for use with a nebuliser device. Also described is finely divided powdered azole antifungal with a mass median diameter in the range 0.1 to 10 microns and a method of prophylaxis of a fungal pulmonary infection which comprises administering by inhalation a therapeutically effective amount of an azole antifungal to a patient predisposed to such an infection.

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